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Bone
morphogenetic protein refers to multifunctional growth factors that
play a crucial role in limb development, repair of cartilage, and
repairing early fracture. Till now, about twenty different bone
morphogenetic proteins have been identified. Each of these bone
morphogenetic proteins exhibits varying degrees of tissue stimulating
characteristics.
Bone
morphogenetic proteins play a significant role in bone augmentation
and bone healing since they ensure rapid healing of fractured bones.
The roles played by these proteins have most importantly been
observed in spinal fusion. There is a greater possibility of bone
morphogenetic proteins being used in patients who are either
undergoing complicated spinal fusion procedures, or those patients
who have previously undergone surgery.
Orthopedic
researches primarily aim at developing techniques for promoting rapid
bone reconstruction and make them functionally stronger. Recent
orthopedic research and studies have shown that bone morphogenetic
proteins like rhBMP-2 have the capacity to stimulate a patient’s
cells to create more bone. Bone morphogenetic protein is especially
beneficial for those patients who are undergoing spinal fusion
techniques since this protein eliminates the need for bone
transplantation from the pelvis.
Importance
and Significance of the Bone Morphogenetic Protein in the Field of
Orthopedics
Almost
one third of the total spinal procedures taking place worldwide are
incorporating bone morphogenetic proteins. The popularity of growth
stimulating spinal cages is being observed in spinal surgeries. The
primary advantage of incorporating bone morphogenetic proteins in
orthopedic procedures is that it does not rely on donated human
tissue. The popularity and efficacy of the bone morphogenetic protein
is gaining much momentum because these days doctors and physicians
are keeping up with the latest developments taking place in the field
of orthopedic medicine.
Moreover,
bone morphogenetic proteins ensure faster bone healing. The bone
morphogenetic protein market is witnessing growth due to rising cases
of fusion failure via the conventional methods. It is also
anticipated that bone graft substitutes will be replaced with bone
morphogenetic proteins in the years to come.
The
global bone morphogenetic protein market will be expanding
significantly in the forthcoming years owing to greater number of
spinal fusion procedures. Rising cases of bone fractures; especially
in the developing economies is a prominent factor that drives the
global bone morphogenetic protein market.
Higher
incidence of spinal anomalies, sedentary lifestyle of the modern day
generation, and a growing global geriatric population are some of the
main factors that fuel the global bone morphogenetic protein market.
Problems
Prevailing in the Bone Morphogenetic Protein Market and the Future of
this Market
A
stark problem facing the global morphogenetic bone market is the high
price of the products available in the market. This is one of the
main factors that will inhibit the growth of the bone morphogenetic
protein market in the developing economies. Another factor that
magnifies the problem is the issue of unfavorable reimbursements.
These problems have to be dealt with soon, in order to ensure
effective market capitalization.
Currently,
the prices of bone morphogenetic proteins are prohibitively high
since their production requires a very expensive type of mammalian
cell. The development of its inexpensive alternatives is a very
cumbersome and a complex process that would entail European and FDA
approval in order to prove its clinical efficacy and safety. Surgeons
are generally hesitant about using bone morphogenetic proteins
because they are quite expensive.
There
are several biocompatibility issues also with regard to bone
morphogenetic proteins. Bone morphogenetic proteins are found
naturally in the human body; however, high concentration of these
proteins poses several carcinogenic and immunological problems. Also,
many a times bone morphogenetic proteins lead to excess bone growth
in locations apart from the site of treatment.
According
to industry analysts, the future of the global bone morphogenetic
protein market relies significantly on the market players adopting
intensive strategies that aim at research and development, end-user
awareness, technology, and business ventures like mergers and
acquisitions.
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